Cancer deaths are largely attributed to tumor metastasis--when the cancer cells spread to other parts of the body--rather than primary tumors. Previous research has shown that OGR1 is expressed at lower levels in metastases than in primary prostate tumors. Lisam Shanjukumar Singh, Ph.D., of Indiana University in Indianapolis and colleagues ...
Previous research had suggested that people who received statins might be less likely to develop Alzheimer’s disease. "But our study is the first to compare the brains of people who had received statins with those who had not," said Gail (Ge) Li, MD, PhD. The paper’s lead author, Dr. Li ...
The findings, to be published Sept. 2 in the online version of Nature Immunology, reveal that, in mice, mast cells help decrease skin damage over time from sun exposure or from poison oak. "These reactions are much worse if mast cells aren’t present," said senior author Stephen Galli, MD, professor and ...
The study followed 192 people with Alzheimer’s disease in New York for an average of four and a half years. During that time, 85 of the people died. Researchers found that those who most closely followed a Mediterranean diet were 76 percent less likely to die during the study period ...
The report, written by primary care experts at the University, indicates that male GPs are more likely to give male patients a larger amount of intermediate sick leave (6-28 weeks) from work compared with female patients certified by female doctors. The study, which is the first of its kind ...
A new study shows that the amount of preparatory muscle action in the muscles spanning the knee joint prior to landings is associated with knee positions that are considered at risk for ACL rupture, said Riann Palmieri-Smith, lead author and assistant professor at the University of Michigan Division of Kinesiology. The ...
In a new study published in the October issue of the Journal of Pediatrics, 86 percent of parents report that they participate in decisions made about their hospitalized child’s medical care. Researchers also found that parents who feel confident communicating with physicians -- as well as those parents whose child ...
Juice from the pomegranate shows promise for fighting prostate cancer. (Credit: USDA Agricultural Research Service) In a new study, Navindra Seeram and colleagues have found that the tart, trendy beverage also uses a search-and-destroy strategy to target prostate cancer cells. In previous research, Seeram’s group ...
In a new Tufts University study, three biologists have challenged that notion by suggesting that people with Huntington’s have more children because they are healthier - not more promiscuous - during their peak reproductive years. "Huntington’s is a disease that may have beneficial health effects on people early in life, ...
Because doctors sometimes have to inflict pain on their patients as part of the healing process, they also must develop the ability to not be distracted by the suffering, said Jean Decety, Professor in Psychology and Psychiatry at the University. "They have learned through their training and practice to keep a ...
The tree bark compound, known as gambogic amide, behaves much like Nerve Growth Factor (NGF), a molecule found in the brain. NGF binds to TrkA, a neuronal receptor, and activates neuronal signaling. It is known that the loss of TrkA density correlates with neuronal atrophy and severe cognitive impairment such ...
In rats with portal hypertension, ultra-low-dose aspirin has shown a normalizing effect of platelet-endothelial cell alterations and bleeding time. Further, this effect is mediated by Cyclooxygenase 2 inhibition. This study, performed by a team led by Professor C. Doutremepuich, is described in a research article published in the ...
The current study is based on previous research carried out on experimental animals. This is a study approved by the Spanish Medication Agency, an official body certifying that the research complies with the legal, ethical and safety requisites of the patient. The patients that are or will be involved in ...
Previous research has linked maternal drinking during pregnancy to several problems in offspring, including conduct problems, criminal behavior, attention and impulsivity problems and alcohol disorders, according to background information in the article. However, new questions have been raised about the strength of the evidence, as some researchers have suggested that ...
Now a report published in Nutrition Journal suggests that even athletes, who should be well informed as to how to stay in peak physical condition, frequently take supplements without realising the potential benefits or side effects. A research team, led by Andrea Petróczi of the School of Life Sciences at Kingston ...
The study included 117 people who developed dementia out of an original cohort of 488. The researchers, led by Charles B. Hall, Ph.D., associate professor of epidemiology and population health at Einstein, followed study participants for an average of six years using annual cognitive tests. Study participants ranged in formal ...
The study, published in Sexual Abuse: A Journal of Research and Treatment, suggests that pedophiles may have been exposed to pre-birth conditions that affected their physical development. The researchers observed this height difference by analyzing the files of over 1,000 men who were assessed for pedophilia or other sexual disorders ...
Principal investigator Giao Tran, UC associate professor of psychology, says the program was geared toward college students who turned to drinking to keep the edge off their anxiety at social gatherings. Tran, along with Joshua Smith, a graduate student for the UC Department of Psychology, and Kevin Corcoran, dean of the ...
"Our studies suggest a quartet of molecules may have potential diagnostic significance," said Dr. Chandra Mohan, professor of internal medicine and senior author of a study available online at the Journal of Immunology. "Given that early intervention in lupus nephritis is associated with better treatment outcome, it is imperative that ...
Led by Mark Wheeler, a psychology professor in Pitt’s School of Arts and Sciences, and conducted at Pitt’s Learning Research and Development Center, the research is a step toward mapping the human decision-making process. This study used an innovative technique and analysis to show that human decision-making is a collaboration ...
The studies looked at premature atherosclerosis in lupus patients as well as accelerated cell death that seems to be behind many of the disease’s symptoms. Lupus is an autoimmune disorder that can involve the joints, kidneys, heart, lungs, brain and blood. An estimated two million Americans have a form of ...
The study, published in the Journal of Psychiatry Research, challenges the commonly held belief that pedophilia is brought on by childhood trauma or abuse. This finding is the strongest evidence yet that pedophilia is instead the result of a problem in brain development. Previous research from this team has strongly hinted ...
Former U. of I. doctoral student K. Todd Keylock, now a professor of kinesiology at Bowling Green State University, prepares wounds for analysis in a laminar flow hood. (Credit: Photo by Susan Herrelr) Now a new U. of I. study points to yet another ...
"We in the medical community have long believed we were caring for these women appropriately and this study determines that these patients over age 65 are being woefully undertreated," said Dr. Owusu, who runs the ICC’s geriatric oncology program and was lead author of the study. "Going forward we need ...
The more miscarriages or abortions a woman has, the greater are her chances of giving birth to a child that is underweight or premature in the future, the research shows. Low birthweight (under 2500 g) and premature birth (less than 37 weeks) are two of the major contributors to deaths among ...
Cancer prevention guidelines recommend earlier and more frequent screening for individuals with a family history of certain cancers. Therefore, knowledge and timely reporting of cancer history can impact access to cancer prevention and screening services. Previous research has identified lower rates of reporting cancer family history among African Americans, Hispanics, ...
Organ transplantation offers the best, and often only hope for long-term survival for patients with end-stage heart, liver, and kidney disease. However, despite federal regulation and national efforts to ensure equal access to the limited pool of donated organs, previous research has demonstrated the presence of significant barriers to ...
According to Temple University’s Joanna Maselko, Sc.D., women who had stopped being religiously active were more than three times more likely to have suffered generalized anxiety and alcohol abuse/dependence than women who reported always having been active. “One’s lifetime pattern of religious service attendance can be related to psychiatric illness,” said ...
"Shivering, which is actually heat production in skeletal muscles, requires quite a bit of energy and is usually the last strategy the body uses to maintain its internal temperature to survive in a severe cold environment. Other strategies to defend against the cold, such as reducing heat loss to the ...
p> While previous research showed a link between caffeine consumption and miscarriage, this is the first study to thoroughly control for morning sickness, which typically causes many women to avoid caffeine, explained De-Kun Li, MD, Ph.D., an investigator with the Kaiser Permanente Division of Research and lead investigator of the study. ...