A recent study from the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill, the Vanderbilt-Ingram Comprehensive Cancer Center and the Sarah Canon Cancer Center in Nashville have identified an unusually high rate of allergic reaction in cancer patients living in the middle South who received ...
The Institute of Medicine estimates that 1.5 million medication errors occur each year in the United States and poor labeling is one cause of the mistakes. While the Food and Drug Administration has some standards on what prescription labels must include, few regulations guide the format of the information, said ...
Researchers at the National Institutes of Health’s National Institute of Mental Health (NIMH) who conducted the study also explained how: Tamoxifen blocks an enzyme called protein kinase C (PKC) that regulates activities in brain cells. The enzyme is thought to be over-active during the manic phase of bipolar ...
A new study from the Southwest Oncology Group strongly suggests that for men at risk of the disease -- which strikes one in six men -- finasteride also raises the odds that physicians will find fast-growing prostate cancers early, when they are most easily treatable. "It appears that a man concerned ...
"We found that over the course of a year, one in six women of reproductive age filled a prescription for a medication labeled by the Food and Drug Administration as increasing the risk of fetal abnormalities," said Eleanor Bimla Schwarz, M.D., assistant professor in the departments of medicine and obstetrics, ...
Two new HPV vaccines are currently being brought to market. Merck’s vaccine -- Gardasil -- was approved federal Food and Drug Administration earlier this year and GlaxoSmithKline’s Cervarix is expected to be endorsed by the agency later this year. The CDC recommends that the ...
Reporting in the October issue of the American Journal of Dermatopathology, the authors suggest a possible explanation for why some patients on kidney dialysis who are injected with a "contrast agent" during a magnetic resonance imaging (MRI) develop nephrogenic systemic fibrosis (NSF). The U.S. Food and Drug Administration now requires ...
While the system, which is made by Nucletron, a technology company based in The Netherlands, is only being used for imaging and planning purposes so far, it ultimately will help with the actual placement of the seeds. To date, Jefferson is the first medical center in the Delaware Valley to ...
Led by Jian Liu, Ph.D., scientists in the UNC School of Pharmacy discovered that they could remove a complex element from the heparin molecule without altering the drug’s function. The component, a single sugar called iduronic acid, is difficult to replicate and was long thought to be an important contributor ...
The catch is that viruses can be infectious and some types of viruses occasionally land in a target genome near an oncogene and raise the risk of cancer. Plasmids don’t carry that risk, but they are not nearly as efficient at reproducing in cells, which is important when the goal ...
A woman at risk for osteoporosis is told by her doctor to get 1,200-1,500 milligrams of calcium every day. But when she looks at the Nutrition Facts panel on a carton of yogurt or a jug of milk, she finds that calcium is only listed by "Percent Daily Value" (%DV). ...
Copaxone® was the first original Israeli drug to be approved by the U.S. Food and Drug Administration (FDA), and is today marketed in over 40 countries worldwide, including the U.S.A., Europe, Australia, Latin America and Israel. The drug molecule was the fruit of research by Prof. Michael Sela, Prof. Ruth Arnon ...
They say that the technique appears to offer a treatment option for patients who develop multiple tumors in their liver from cancer metastasis. "Most of these patients don’t have other effective treatment options, because surgery is not possible if there are multiple tumors in their liver," says the study’s lead ...
The finding is included in a study of chronic medication use in children 5 to 19 reported Wednesday, Nov. 7 at the annual meeting of the American Public Health Association by researchers from the Saint Louis University School of Medicine and School of Public Health and pharmacy benefit manager Express ...
A new NIST-sponsored study found that the biopharmaceutical industry spend a total of $1,219 million on infrastructure technology?884 million on the R&D technology infrastructure including bioimaging, biomarkers, informatics, and gene expression and $335 million on infrastructure for commercial manufacturing and postmarket surveillance. (Credit: NIST) Prepared ...
"The fact that we have a technology where the outcomes in women are equal to men is important," said Roberta C. Bogaev, M.D., lead author of the study and medical director of heart failure and cardiac transplantation at the Texas Heart Institute in Houston. "Historically, because of their size, ...
Licensing of new drugs in Europe is increasingly controlled by the European Medicines Agency (EMEA), yet new drugs have only to show they are equivalent to current treatments rather than show superiority. This favours the interests of drug companies, say Silvio Garattini and Vittorio Bertele from the Mario Negri Institute ...
It suggests that long-term administration of the drug captopril, starting at three weeks after patients receive total body irradiation in preparation for bone marrow transplantation (BMT), showed a favorable trend for better long-term kidney function and better long-term patient survival. Chronic kidney failure continues to be a major complication in ...
Currently, TB patients must adhere to a complex treatment regimen over a six- to nine-month period. This demanding schedule often results in patients skipping treatment doses, which has given rise to drug-resistant strains of M. tuberculosis, including multi-drug-resistant (MDR) and, more recently, extensively drug-resistant (XDR) TB. SQ109, an antimicrobial agent developed ...
Fibromyalgia affects approximately 3.4 percent of women and 0.5 percent of men in the United States, according to background information in the article. Patients with fibromyalgia experience chronic pain throughout their bodies for at least three months, along with specific sites of tenderness. Causes and mechanisms are poorly understood. "Even ...
The vaccine, called nine-valent, is being compared with Gardasil, a quadrivalent vaccine already on the market that works against the two most deadly HPV types. “We’re testing Gardasil against three different doses of the investigational vaccine,” says Dr. Daron Ferris, family medicine physician and director of the MCG Gynecologic Cancer Prevention ...
The new study reports pre-clinical evidence that the newly re-engineered drug is just as effective as imatinib against gastrointestinal stromal tumor (GIST) and carries significantly less risk of heart failure. Developed by Novartis Pharmaceuticals, Gleevec is approved by the U.S. Food and Drug Administration for the treatment of chronic myeloid leukemia ...
Dr. Gary Lemack talks with Lynette Kunz about a procedure to regain bladder control using Botox. Researchers are recruiting study participants for a Botox clinical trial investigating urological conditions. (Credit: Image courtesy of UT Southwestern Medical Center) “I can somewhat detect when my bladder is ...
The thiazolidinediones (TZDs) rosiglitazone and pioglitazone are oral hypoglycemic agents used to treat type 2 diabetes and have been shown to improve glycemic control. "While improved glycemic control has been linked to better clinical outcomes in diabetes and TZDs have been suggested as having potential cardiovascular benefits, recent concerns have ...
All patients in both trials have a complete cytogenetic response - absence of the aberrant chromosome that causes the disease - after one year on either drug. Approximately 90 percent reach complete cytogenetic response as early as 6 months. "These are early results but certainly encouraging so far in both cases," ...
Dementia is an ever-increasing problem in today’s aging societies, with millions of patients and their carers affected worldwide. About one in five people over the age of 80 suffers from Alzheimer’s disease, the most common type of dementia. There is no cure and little hope is available for treatment, thus ...
Cardiovascular disease is the leading cause of death and disability among Medicare beneficiaries, according to background information in the article; expenses for this condition exceed those for any other. "Because Medicare expenditures continue to increase rapidly, it is necessary that coverage decisions be based on data most likely to maximize ...
Howard Bassen, a researcher with the U.S. Food and Drug Administration in Rockville, Md., led a research team that measured the magnetic fields produced by four different iPod models: a fourth-generation iPod and an iPod with video, and an iPod nano and iPod shuffle. They also measured the voltages ...
Turner and his colleagues examined reviews from the Food and Drug Administration (FDA) for trials of 12 widely prescribed antidepressant drugs approved between 1981 and 2004, involving 12,564 patients. They also conducted a systematic literature search to identify whether results of these studies had been published in medical journals. ...
The technique, called radioembolization, has been approved by the federal Food and Drug Administration for use in inoperable liver cancer. This is the first time that the particular technology, called SIR-Spheres microspheres, which is FDA-approved for treating colon cancer that has spread to the liver, is being studied in patients ...