Cedric F. Garland, Dr.P.H., cancer prevention specialist at the Moores Cancer Center at the University of California, San Diego (UCSD) and colleagues estimate that 250,000 cases of colorectal cancer and 350,000 cases of breast cancer could be prevented worldwide by increasing intake of vitamin D3, particularly in countries north of ...
Animal studies have shown that DIM -- a chemical produced when vegetables such as broccoli, cabbage and kale are chewed and digested -- can actually stop the growth of certain cancer cells. (Credit: iStockphoto) Veggie fans can already point to some cancer-fighting properties of ...
Their study, published in the August 1 issue of the Journal of the National Cancer Institute, found that the relative risk of developing breast cancer in post-menopausal woman with dense breasts was 400 percent higher than in women with fatty, non-dense breast tissue, and that high versus low levels of ...
The cancer biology team from UQ’s Diamantina Institute for Cancer, Immunology and Metabolic Medicine, believe their finding will help explain the link between breast cancer and high levels of estrogen. "What we’ve shown is that the ability of estrogen to switch this gene on is important for the growth of ...
Acrylamide, a compound found in a variety of widely-consumed foods ranging from French fries to coffee, does not appear to cause breast cancer, researchers report. (Credit: American Chemical Society) "At levels consumed in the diet, it appears unlikely that acrylamide in foods is related ...
A hot flash is often described as a flush of intense warmth across much of the body that may be accompanied by sweating, reddening of the skin, or, occasionally, cold shivers. Hot flashes occur in varying frequency and duration, even during sleep, and often cause or accompany sleep deprivation, anxiety ...
Breast cancer surgery patients often suffer side effects such as pain, nausea, and fatigue during and after their operation. These complications can lengthen their hospital stay, lead to hospital readmission, or require additional medications--all of which increase medical costs. Several previous studies have suggested that hypnosis may reduce pain, recovery ...
The findings, published in the September 1 issue of Cancer Research, a publication of the American Association for Cancer Research, suggest that genes which influence breast density could serve as a predictive marker for disease and provide a biological target for agents that may reduce breast cancer risk by reducing ...
The study involved male mice that were fed a plant compound found in red wine called resveratrol, which has shown anti-oxidant and anti-cancer properties. Other sources of resveratrol in the diet include grapes, raspberries, peanuts and blueberries. In the study resveratrol-fed mice showed an 87 percent reduction in their risk of ...
Michael Reed, MD, and William Zagorski of UC’s surgery department study the role of the RB tumor suppressor in lung cancer. (Credit: Image courtesy of University of Cincinnati) Known as the retinoblastoma (RB) tumor suppressor, this fundamental molecule regulates cell proliferation in the body. Research ...
Scientists have found that the aluminium content of breast tissue and breast tissue fat was significantly higher in the outer regions of the breast, in close proximity to the area where there would be the highest density of antiperspirant. Recent research has linked breast cancer with the use of aluminium-based, ...
Resistance and aerobic exercise In the first study, Canadian investigators explored the effects of exercise on quality of life, physical fitness and body composition in women receiving chemotherapy for early-stage breast cancer. This study, the Supervised Trial of Aerobic versus Resistance Training (START) trial, is the largest to date ...
Yuxin Feng, David Manka, PhD, and Sohaib Khan, PhD, have developed a estrogen receptor gene knock-out mouse model. (Credit: Image courtesy of University of Cincinnati) About a decade ago, U.S. scientists at the National Institutes of Health (NIH) developed a standard estrogen receptor (ER) ...
"This is the first prospective study to report a significant association between alcohol and endometrial cancer," says Veronica Wendy Setiawan, assistant professor of preventive medicine at the Keck School of Medicine of USC. "Previous studies have shown that alcohol consumption has been associated with higher levels of estrogens in postmenopausal ...
The women in the study were taking aromatase inhibitors, a type of drug designed to block the production of estrogen, which fuels some breast cancers. The treatment is generally given after surgery, chemotherapy or radiation therapy to prevent the cancer from returning. It’s typically prescribed as one pill each day ...
Each predictor - of prognosis, of sensitivity to chemotherapy and sensitivity to hormone therapy - is independent of the others, providing unique information to physicians and patients considering treatment options, says W. Fraser Symmans, M.D., professor in M. D. Anderson’s Department of Pathology. "Existing genomic tests for breast cancer provide information ...
“A V/Q scan can be the first choice—but the CT angiogram is the classic choice—for diagnosing a pulmonary embolism,” noted H. Dirk Sostman, a professor of radiology and executive vice dean at Weill Cornell Medical College in New York City and chief academic officer at the Methodist Hospital in Houston, ...
ER-negative tumors are associated with less favorable outcomes than those that are ER-positive, in part because anti-estrogen therapies—effective with ER-positive tumors—do not affect ER-negative tumors. The overall incidence of breast cancer in black women is lower than in white women, but survival rates are significantly lower in black women than ...
Fatigue is a common complaint in the general population and, anecdotally, common among cancer patients. Comparative fatigue studies between the two populations, however, have been marred by methodological shortcomings, such as poorly matched controls and patient populations. The studies do not consistently agree whether or not fatigue is a more ...
Researchers at the National Institutes of Health’s National Institute of Mental Health (NIMH) who conducted the study also explained how: Tamoxifen blocks an enzyme called protein kinase C (PKC) that regulates activities in brain cells. The enzyme is thought to be over-active during the manic phase of bipolar ...
That paradox has led scientists to question exactly how, or if, estrogen is involved in cancer development and whether removal of ovaries makes sense. Now, a team of researchers from Georgetown University’s Lombardi Comprehensive Cancer Center have shed light on the mechanism that makes ovary removal protective against tumor development ...
Estrogen causes hormone-responsive breast cancer cells to grow and divide by interacting with estrogen receptors made by cancer cells. Interfering with estrogen signaling is the basis of two common breast cancer therapies -- tamoxifen, which blocks estrogen’s interaction with a primary estrogen receptor called ER-alpha, and aromatase inhibitors that reduce ...
Susan Greenspan, M.D., director of the Osteoporosis Prevention and Treatment Center and Bone Health program at the University of Pittsburgh Medical Center, and colleagues evaluated 87 women, mean age 50, enrolled in the Prevention of Osteoporosis in Postmenopausal Women with Breast Cancer Following Chemotherapy study. All participants in the randomized, ...
Additionally, the women were able to correctly identify the possible benefits and risks linked to hormone therapy just 40 percent of the time. Senior author Randall Stafford, MD, PhD, associate professor of medicine at the Stanford Prevention Research Center, said the new study points out that the medical profession hasn’t yet ...
The clinical practice article, a regular NEJM feature that focuses on a case history highlighting a common clinical problem, was authored by Glenn D. Braunstein, M.D., chair of the Department of Medicine at Cedars-Sinai Medical Center and an expert in gynecomastia and other hormone-related diseases. "Nearly half of all ...
Now, for the first time, a group of scientists have shown that they can also detect CTCs before and after chemotherapy treatment and hence may be able to identify those patients likely to have a recurrence of their cancer after such treatment in future. Dr. Julia Jückstock, from the University of ...
Utilizing a process called x-ray crystallography, the scientists solved the structure of the large PKA complex, revealing a totally new structure that shows PKA’s amazing ability to function as a "scaffold," that supports and controls the release of chemicals involved in transmitting signals. The structure is shown in the ...
Dietitian Katrina Campbell, who graduated with her PhD from QUT yesterday, monitored the diets of 62 pre-dialysis patients at the Royal Brisbane and Women’s Hospital (RB&WH) and supported them with regular contact as part of her thesis. Dr Campbell said depending on the patient’s individual situation, a dietitian could intervene by ...
Dr Rafael Rosell told the European Cancer Conference in Barcelona September 25, that analysis of the expression of five different genes had shown that those NSCLC patients who had high levels of expression of BRCA1 had nearly double the risk of dying early from the disease than those patients with ...
A new study published in the Sept. 24 issue of the Archives of Internal Medicine raises serious questions about the hefty costs and uneven content of these already controversial examinations. In the first study to systematically quantify the number, cost and content of preventive health and preventive gynecological exams, the ...